No one likes pain sensations – they cause severe discomfort, because of pain a person cannot lead a normal life and fully enjoy it. Fortunately, it is quite simple to cope with the pain syndrome today – pharmacies offer a large selection of painkillers that help not only alleviate the condition, but also prevent the recurrence of unpleasant painful sensations.
It is rather difficult to understand the huge range of these drugs: they differ from each other in terms of the principle of action, the active substance used, the available contraindications and possible side effects. The main thing to remember when buying painkillers is that they must be prescribed by your doctor. Without his recommendation, it is undesirable to purchase such drugs. Our ranking of the best pain pills presents the most popular drugs among patients. First of all, when compiling this review, we relied on user reviews, as well as the value for money of products.
Top 10 Pain Relief Pills
10. Nurofen Long
A well-known pain reliever that has a directional effect. Tablets are a synergistic drug that can significantly enhance the activity of antipyretic and analgesic drugs. Due to this, their efficiency is increased several times. Initially, these tablets were used to combat headaches, as well as various discomfort that accompanies various kinds of inflammatory processes. Two substances are used as active ingredients here – ibuprofen and paracetamol. The first has a depressing effect on pain receptors, and also has a pronounced antipyretic effect. It is used to combat inflammatory processes of various origins. Ibuprofen inhibits the activity of acetylsalicylic acid and all its derivatives, reversibly inhibits platelets. Paracetamol activates the hormone serotonin and hydrositripamine-5, which will suppress pain signals directly in the canals of the spinal cord. Used to combat migraine, toothache.
The combination of components in the drug is selected in such a way that the effectiveness of the drug in particularly acute pain is 93.2%, the tablets quickly reduce sensitivity in chronic pain. The drug begins to act approximately 18-20 minutes after ingestion, the activity of the drug reaches 9.5 hours. The metabolic reaction of active substances is quite pronounced. Part of paracetamol is excreted naturally through the kidneys, about 5% leaves the body unchanged. Part of the drug is deposited in the liver, where it then decomposes into harmless compounds. All active components are released from the drug at the same time, which has a positive effect on the effectiveness of the drug. Tablets allow you to quickly get rid of rheumatic pains, cope with mild and moderate arthritis. They fight well with toothaches, as well as discomfort that occurs in the gums due to dental intervention. There are few side effects – nosebleeds, slight swelling of the face or larynx.
- Widespread remedy;
- Two active components are used at once;
- Quickly relieves pain syndromes;
- Possesses long action;
- Does not accumulate in the body.
- Pain from arthritis or severe rheumatism dulls, but does not completely go away;
- There are a number of contraindications and side effects.
A complex remedy, characterized by a rather pronounced analgesic and antispasmodic effect. Produced in the form of tablets, coated with a green film shell. The preparation contains the following substances – paracetamol, caffeine, naproxen, drotaverine hydrochloride and pheniramine maleate. Naproxen is a substance that belongs to the group of non-steroidal anti-inflammatory drugs. It also has antipyretic and analgesic properties. Under its action in the patient’s body, the production of prostaglandins, which act as mediators of the development of inflammatory processes and pain, slows down. Caffeine additionally expands the vessels of the heart and other internal organs, tones the vessels penetrating the brain. Under the influence of caffeine, the patient’s lethargy and drowsiness decrease, and working capacity increases. Drotaverine hydrochloride is used to relieve spasms. In addition, it relaxes the smooth fibers of the muscle tissue surrounding blood vessels and many internal organs. Pheniramine is also designed to get rid of spasms and swelling, it also enhances the effect of other substances contained in this medicine, its action is aimed at calming the nervous system. Pentalgin successfully fights pain syndrome, regardless of its nature – in addition to toothache or menstrual pain, it copes well with hepatic and renal colic, relieves discomfort during an exacerbation of gallstone disease. It is often used as part of complex therapy to combat fever and fever.
There are quite a few restrictions on its use, so you will have to consult with your doctor without fail, and before taking the medicine, you should carefully study its annotation. It is strictly prohibited for any chronic diseases of the gastrointestinal tract – for gastritis, gastric and duodenal ulcers. If there is even the slightest suspicion of bleeding in the digestive canal, then the use of pentalgin should also be abandoned. Often there is an individual intolerance to some components. This medicine should not be used during pregnancy and breastfeeding, the same applies to children and adolescents under 14 years of age. To achieve the maximum effect, the drug should be taken one tablet three times a day – the frequency of use directly depends on the level of pain severity. It should be borne in mind that an adult is allowed to drink a maximum of 4 tablets per day, do this strictly after meals. This allows you to prevent irritating effects on the walls and mucous membranes of the gastrointestinal tract.
- Quickly relieves any, even fairly severe pain;
- Copes well with fever and fever;
- Easily combined with other drugs;
- Acceptable cost.
- There are a lot of contraindications.
A non-steroidal anti-inflammatory type of medication – such drugs are quite popular today with both doctors and patients. This tool allows you to quickly get rid of any pain, helps to cope with ailments associated with colds and flu. Naprexen sodium is used as the main active ingredient here. Release form – blue capsules, film-coated. Before use, be sure to read the instructions. During the flu, the medicine reduces the temperature, relieves muscle pain, stabilizes well-being, helps to overcome weakness and general malaise. The drug is suitable for people experiencing severe back pain, suffering from migraines, including chronic ones, excellently fights against pain in the teeth and gums. Well relieves pain during menstruation, relieves discomfort during sciatica, arthritis. However, it should be borne in mind that the drug relieves only of the consequences of the pathology, without affecting its cause, so after some time the pain will return again. With increased sensitivity of the body in relation to the active substance, it is necessary to stop taking this medication. It is also prohibited for pregnant and lactating women, children are allowed to give it from the age of 9.
After surgical interventions, it is also forbidden to take. This medication is discarded if the patient suffers from a stomach ulcer, various inflammatory processes in the intestines. The action of the tablets lasts for 4-8 hours, depending on how severe the pain is. With a cold, the drug is allowed to take no more than 3 days, but if the medicine is intended to relieve pain, then the period can be increased by up to 5 days. It is often used as a prophylactic to help prevent the onset of migraine – therapy can take up to 2 weeks, but in this case you will need to be regularly monitored by your doctor.
- Broad effect of the drug – fights colds, acts as a preventive medicine, copes with pain;
- Only one substance acts as an active ingredient;
- Starts to work quickly.
- Often there is individual intolerance.
The preparation contains the following substances: non-narcotic analgesic metamizole sodium, pitoferon, which is a myotropic antispasmodic compound, fenpiverinium bromide, which is responsible for the m-anticholinergic effect. Metamizole is a compound that is a derivative of pyrazolone. It has a pronounced antipyretic, analgesic and anti-inflammatory effect. The action of pitofenone is similar to papaverine – it gently relaxes smooth muscles, gently relieving spasm. Fenpiverinium bromide enhances the action of these active compounds. Together, the components of the drug reduce the temperature, reduce the pain effect. Experts advise using spasmalgon for mild or moderate pain syndrome, which occurs, including with renal or hepatic colic. It is recommended for a one-time reduction of pain in the joints, with neuralgia, myalgia. It is used to alleviate the patient’s condition after interventions of a surgical or diagnostic nature.
The drug is suitable for children over the age of 6 years, however, you will have to follow a certain dosage indicated in the annotation to the drug. There are some side effects – dry mouth, lowering blood pressure. The medicine can cause allergic reactions.
- Complex effect on the body;
- Quickly copes with pain;
- Long lasting positive effect.
- Physical and mental reactions may decrease, so you should not drive while using this remedy.
6. Diclofenac tab. on
A very popular drug designed to combat joint pain. It also relieves inflammation in muscle tissue. It is produced in several formats – ointment, tablets, capsules. To date, this product is one of the most powerful painkillers. It is worth noting that only a gel or ointment can be purchased without a prescription, drugs for internal use are released strictly on the recommendation of a doctor. This medicine is well suited for the elderly, who often suffer from pain in the muscles and joints. It is worth noting that the drug also has antipyretic characteristics. According to the chemical composition, the most active component of this drug belongs to the derivatives of acetic acid. It often helps people when other drugs can no longer cope. Diclofenac is able to cope with even the most severe pain, although it was originally developed as an anesthetic for mild to moderate syndrome. The mechanism of action of such a drug is based on the suppression of the body’s production of substances that trigger inflammatory processes. Thanks to this, not only does the pain decrease, but the swelling also disappears.
If you take the drug for a long time, then antihistamine qualities also appear – the key components that are in the composition enter the circulatory system, and through it they penetrate into the synovial fluid, which is located in the joints themselves. After a cycle of treatment, the pain syndrome can be forgotten for a long time.
- The optimal medicine for older people suffering from joint pain;
- Acceptable cost;
- Copes well even with severe pain;
- After completing the course of treatment, you can forget about the pain for a long time;
- Has good antipyretic qualities;
- It copes where other drugs are already powerless.
- The tablets are sold by prescription only;
- A decent amount of far from the most pleasant side effects.
diclofenac tab. on
5. Artromaximum Martinia
The first biologically active food supplement in our review, whose action is aimed at reducing pain in the joints and preventing such a disease as gout. Produced in the form of capsules. The main active substance is a dry extract of martini fragrant, it also contains a whole range of various food additives – microcrystalline cellulose, magnesium stearate, iron oxide and gelatin. The agent can inhibit the onset of the inflammatory process directly at the cellular and molecular level. Due to the original characteristics and balanced composition, with the regular use of such a drug, it is possible to reduce muscle tension. In the joints, the concentration of uric acid gradually decreases, which just leads to the onset of gout. If you take the drug regularly, then not only pain will decrease, but the flexibility and mobility of the joints themselves, including the spine, will increase. Literally in the first week, swelling disappears, a person becomes more active.
There are practically no contraindications here – you can not take the drug for pregnant and lactating women and people who are sensitive to one of the components of this remedy.
- Quickly absorbed by the body;
- Can be taken for a long time;
- It also acts as a prophylactic;
- It relieves pain well.
- Quite often there is an individual intolerance to the drug.
This drug is known to every person, since it was developed back in Soviet times, however, even to this day it has not lost its relevance. The analgesic effect is achieved thanks to metamizole sodium. The remaining substances contained in this medicine are auxiliary and do not play a special role in relieving pain – these are potato starch, sugar, calcium stearate and talc. Available in the form of tablets that have a white or yellowish color. The medicine tastes very bitter. According to the generally accepted specification, the drug is a non-steroidal agent with a pronounced anti-inflammatory effect. According to the mechanism of work, analgin is practically no different from other painkillers. It quickly blocks the inflamed nerve receptors, providing a reduction in pain. It fights inflammatory processes weakly, so it practically does not affect the exchange of salts and water in the body, and also does not irritate the mucous membranes of the gastrointestinal tract.
This tool can be taken even by young children, starting from the age of three months in the form of a solution. However, for people with diseases such as bronchial asthma, as well as for blood diseases, analgin is contraindicated. Taken twice a day after meals. You should not exceed the recommended dosage, as this can lead to various side effects, in particular, allergic reactions and a decrease in blood pressure.
- Inexpensive and widespread tool;
- Effectively fights with any kind of pain syndromes, including postoperative ones;
- Suitable for children over the age of 3 months;
- Also available as an injection.
- Not very long exposure.
3. Ketoprofen organic tab. p.p.o.
It is a derivative of propionic acid. Together with painkillers, it also has an anti-inflammatory and antipyretic effect, which allows it to be treated during colds. The mechanism of action is quite standard, but there is also an original point here – the active substance significantly slows down the production of prostaglandins in the nervous system (both in the central and peripheral), which are responsible for the spread of pain, the transmission of information about it to the spinal cord and brain. It also affects other neutrotropic substances that can release pain mediators. As a result, it turns out that this medicine not only relieves the pain syndrome, but masks it for a while. However, with the help of the remedy, it is possible to reduce puffiness.
Works well with diseases such as arthritis and gout. Pain is relieved almost instantly – the drug begins to act in just 5-7 minutes after ingestion. These pills can also relieve pain in the spine, alleviate the condition of patients with myalgia and neuralgia. With uncomplicated injuries, which include dislocations, sprains, bruises of various kinds, the effectiveness of the drug is much higher. Often, ketoprofen can be used in the combined treatment of inflammatory processes in the veins, lymph nodes and blood vessels. This is one of the few remedies that are allowed for pregnant women (with the exception of the last trimester).
- Copes well with diseases of the joints associated with severe pain;
- Used as a therapeutic agent.
- In fact, it simply masks pain, although it relieves swelling, so after the end of the period of action of the drug, the pain will most likely return.
Ketoprofen organic tab. p.p.o.
In second place in the review of the best painkillers pills is another very well-known medicine in people, which effectively and for a long time copes with pain, and also allows you to relieve swelling and stop inflammation. Available in several forms, which makes it the most convenient to use. However, contraindications must be remembered, since if taken uncontrolled, this medicine can cause a large number of very unpleasant consequences. It must be appointed by a specialist. The composition of the tablets can be different, they are united only by the active substance – nimesulide. It belongs to the group of sulfonanilide derivatives, the compound was discovered quite a long time ago, however, even today it is actively used in pharmacology. It belongs to non-steroidal anti-inflammatory substances.
All other compounds that make up these tablets are auxiliary, do not have an active effect – these are cellulose, starch, talc, calcium, magnesium and silicon compounds. Inflammatory processes slow down quite quickly, and severe pain symptoms subside. The drug is effective for all types of pain, in terms of its effectiveness it is much better than ibuprofen, diclofenac, acetylsalicylic acid, and this applies not only to pain relief, but also to reducing fever. The active substance is able to penetrate into the female reproductive system, as well as into the synovial fluid of the joints, so the drug is used in various areas of medicine – gynecology, orthopedics, traumatology and surgery.
- High drug activity, which manifests itself very quickly;
- It is used in many branches of medicine;
- Good antipyretic effect.
- There are contraindications and side effects;
- In the form of tablets, it is not very common.
1. Brustan tab. p.p.o.
The function of pharmacologically active substances in this medicine is performed by two drugs – ibuprofen and paracetamol. There are many more components, but these are the main ones. The ratio of the compounds is chosen in such a way as to maximize the duration of the drug, effectively drown out pain and overcome even the most serious inflammatory processes. Tablets also cope with fever, allow a person to return to work, relieve him of the symptoms of respiratory diseases. On sale you can find this drug in the form of a syrup – it can be given to children from the age of two. It helps well to cope with the body’s reactions to various kinds of vaccinations, for example, from hepatitis or influenza. The optimal effect is achieved when pain of low or moderate intensity occurs. In particular, tablets easily fight any migraines, relieve toothache. With the help of such a medicine, you can even get rid of pain in the throat and ears during sprains.
Do not take the remedy if the patient has stomach or intestinal ulcers, asthma or rhinitis. The drug is drunk three to four times a day, one tablet every 7-8 hours. If it is used as an antipyretic, then it is allowed to take a maximum of three days, with anesthesia – up to 5 days.
- Combined drug;
- Effectively copes with pain and symptoms of colds;
- It is well tolerated by both adults and children.
- The tablets are large – it is not very convenient to swallow them;
- The drug is prohibited for peptic ulcers of the gastrointestinal tract.
Brustan tab. p.p.o.
In conclusion, a useful video
Our ranking of the best painkillers is over. I would like to believe that you were able to choose for yourself the ideal remedy that will help you cope with discomfort and discomfort in the shortest possible time. If some points need clarification, or if you want to share your impressions of the use of a particular drug, then you can always do this in the comments to this article.